24th Oct, 2018
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Cancer is a systemic disease with tumors as a local manifestation of the disease. Once cancer occurs in a person, cancerous cells will be found in the body. Surgical removal of tumors in no way implies that one is cured of cancer. For example, breast cancer can relapse even if the original tumors were removed.Like hypertension and diabetes, cancer is a chronic disease. The disease may take a few years to manifest itself - from its occurrence until the emergence of tumors. In some cases, cancer cells may exist in a stage of ....
“China Has Taken the World’s Leading Post in the Field of Cryosurgery”-from the Exclusive Interview of Nikolai N. Korpan, a World-Renowned Leading Authority of Cryosurgery from Austria_events_fuda news_Fuda Cancer Hospital Guangzhou_Cancer Treatment China_Tumor Technology_广州复大肿瘤医院_癌症治疗_微创治疗_癌症疗法
“China Has Taken the World’s Leading Post in the Field of Cryosurgery”-from the Exclusive Interview of Nikolai N. Korpan, a World-Renowned Leading Authority of Cryosurgery from Austria
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The first case in China of a cryonics (the practice of freezing a person who has died of a disease in hopes of restoring life at some time in the distant future) "patient," Zhan Wenlian, was recently released on Chinese news sites.  This news has aroused enormous public curiosity and wide-ranging discussions have ensued regarding hypothermal medicine and relevant technology.

It is theoretically known, however, that besides the concept of low-temperature preservation, hypothermal medicine has sometimes presented "hypothermal damage," as in related procedures, such as cryosurgical ablation that has been widely used in treatments of multi-type cancers.  In medical circles around the globe, the death of cancer cells by using the freeze-thaw system of the Argon-helium Knife is considered an accepted, proven, treatment method.

Professor Nikolai N. Korpan, a world-renowned Austrian expert in cryotherapy, recently visited China.  While visiting, he continuously praised China's booming development and substantial achievements in the field of cryosurgery over the past several years. Yesterday, on behalf of Guangzhou Fuda Cancer Hospital, I had a face-to-face exclusive interview with Professor Korpan regarding his work in the field of cryosurgery.


Founder of International Society of Cryosurgery (ISC) and the President of the16th ISC


Professor Korpan recalled:  "It has been almost more than 30 years since I first learned about hypothermal medicine in 1982."  Nikolai Korpan, I believe, must be quite a familiar name to physicians working in the field of minimally invasive cancer therapy. As a surgeon who has served in Rudolfinerhaus, a world-renowned "ancestor-class" surgical hospital in Austria, for over 35 years, Professor Korpan is indisputably deemed the most admired expert in cryosurgical ablation, not only for his rich surgical experience, but also for his plethora of scientific research achievements in this field.

Modern cryomedicine first emerged in Europe and some other developed countries in the 1970's. When Professor Korpan first learned of cryomedicine, he was strongly aware that a great deal more research and relevant research literature was needed.

Professor Korpan said, “At the very beginning, I conducted several animal experiments on dogs' hepatic and pancreatic tumors and collected some relevant experimental data. From repeated data analysis, I could surely see the possibility of cryosurgical ablation in treatment for human body tumors."

During the following thirty years, Professor Korpan devoted himself to a variety of cryosurgery technology research and participated in nearly 20 cases of successive animal experiments, with the intention of analyzing practical applications of cryosurgical ablation in treating human cancer-related diseases, according to massive data pertaining to his years of animal experiments and relevant research. During this period, Professor Korpan successfully published a total of more than 300 papers on cryotherapy, which greatly enriched associated research on cryomedicine, to some extent, at the time. Limited by development of previous radiological technology, however, cryosurgical ablation could only be applied in clinical treatments of human brain tumors in their earliest stage.    

In 2001, Professor Korpan compiled and published Basics of Cryosurgery, the first medical monograph that provided an integrated and comprehensive introduction on the basic knowledge of cryosurgery in the world, thus far (this book is also reputed as the “Bible” of cryosurgery). There is no doubt that Professor Korpan's contributions to cryosurgical ablation have firmly established his academic status in this field worldwide. In 2011, he established the International Society of Cryosurgery and at one time served as its president.

Dr. Niu Lizhi, Vice-President of the Asian Society of Cryosurgery (ASC), once commented, "There is absolutely no-one better than Professor Korpan to be praised as the pioneer, as well as the founder and developer of cryosurgery throughout the world."

Advantages of Cryotherapy

During a long-term period of research on clinical cases and animal experiments, Professor Korpan discovered some incomparable advantages of cryosurgery that conventional surgical treatments failed to achieve in the treatment of some types of cancer. Professor Korpan stated that, “Cryosurgery is a minimally invasive procedure that inflicts fewer traumas than those in conventional surgeries. In addition, it is believed that cryosurgery can effectively minimize the risk of distant metastases that usually occur during traditional surgical resections.  This is because the dead cancerous tissues are not necessarily removed after cryosurgery.”

Professor Korpan introduced that with further advancement of radiological technology, a successful procedure of cryosurgical ablation usually needs to be conducted under the guidance of real-time imaging techniques like B ultrasound, CT scan or MRI scan; this means a great demand for perfect cooperation between radiologists and chief surgeons who have the ability of precisely locating cancerous tissues and sparing normal tissues around tumor margins from damage during the therapeutic process.   

Following the 13th Chinese Academic Conference of Minimally Invasive Therapy in Oncology that just ended, a group of experts and scholars from different countries and regions were brought together to have an all-round exchange and in-depth discussion about the achievements of prospective studies on minimally invasive therapies, including development of Asian cryosurgery. During the conference, Professor Korpan delivered a keynote speech and concluded with relevant clinical cases and data reports of cryosurgical ablation in treating diseases like melanoma and breast tumors, and affirmed the remarkable curative effects of a combined use of cryosurgery and chemotherapeutics in treatments of multi-type cancers.


Prof. Korpan delivered a keynote speech at the 13th Chinese Academic Conference of Minimally Invasive Therapy in Oncology

"Through previous research, I surely found that patients with liver cancer, pancreatic cancer, breast cancer, skin cancer, stomach cancer, and colon cancer enjoy a higher five-year survival rate after cryosurgical ablation. It was statistically shown that the longest survival time of pancreatic cancer patients who had cryosurgical ablation reached seven years, which include all of my previous clinical cases and patients who were once treated at FUDA, as far as I know. I have every reason to believe that this therapeutic method will become a prevalent trend in treatment of early-stage cancer in the future."   


Korpan’s story with Xu Kecheng and his “Medical Kingdom” Guangzhou Fuda Cancer Hospital

Someone may wonder how an Austrian scholar could develop a close liking for a hospital in China. For this, Professor Korpan answered with a smile, “I actually got to know Professor Xu at an academic conference in Beijing during 2003. At this meeting, we discussed some researches on one of my published monographs on cryosurgery. From the talk, I learned about Xu’s great desire to introduce cryosurgery in China; in order to achieve this purpose, he had even established a hospital specialized in cancer treatment in Guangzhou, China. His hope was to firstly begin relevant research on cryosurgery in mainland China. I must say 'Thanks' to the conference; Professor Xu and I would have missed a great chance to find a lifetime friend of like mind.”

Professor Korpan (left) took a photo with Professor Xu Kecheng (right)


Over the next few years, Professor Korpan always paid a special visit to China to meet Professor Xu and discuss the latest advancements in cryosurgery with his “old Chinese friend”. Professor Korpan, of course, has invited Professor Xu to Austria for study visits to discuss the development of local cryosurgery technology. This couple of “old friends” always regrets not having met each other earlier, because they never run out of things to talk about.

In 2013, Professor Korpan handed over his official post as President of the International Society of Cryosurgery (ISC) to Professor Xu Kecheng. From that moment, the scientific research team of Guangzhou Fuda Cancer Hospital, led by Professor Xu Kecheng, ushered into a new era of China’s cryosurgery.

Professor Korpan paid a special study visit to a few hospitals in Shenzhen, China with Professor Xu Kecheng.  He astonished us with his candor, when expressing the following:  "From my visit of these past few days, I can see the substantial achievements in the development of cryosurgery in China during the past several years.  What greatly surprises me is the increasingly integrated data collection that you possess.  To put it bluntly, China's current cryosurgery-related achievements in scientific research have even surpassed some developed countries in Europe and the United States.

Professor Korpan noted that there have been more and more hospitals in China actively introducing and adopting cryosurgical ablation in treatment of many types of cancer; he also observed that China’s doctors showed an unprecedented taste for cryosurgery technology. “I felt quite gratified when I visited the International Cryosurgery Centers, especially established in some of Shenzhen's hospitals, and learned about their relevant research programs in progress.” said Professor Korpan.   



Prof. Korpan was invited to have a symposium with FUDA’s patients during his study visit in Guangzhou


“I dare to say without any hesitation that China has become one of the most advanced countries in cryosurgery technology throughout the world, and it is, of course, because Guangzhou Fuda Cancer Hospital has made an indelible contribution to its development,” Professor Korpan claimed with sincerity.    

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